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Real-time tracking of cell cycle progression during CD8(+) effector and memory T-cell differentiation

The precise pathways of memory T-cell differentiation are incompletely understood. Here we exploit transgenic mice expressing fluorescent cell cycle indicators to longitudinally track the division dynamics of individual CD8(+) T cells. During influenza virus infection in vivo, naive T cells enter a...

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Detalles Bibliográficos
Autores principales: Kinjyo, Ichiko, Qin, Jim, Tan, Sioh-Yang, Wellard, Cameron J., Mrass, Paulus, Ritchie, William, Doi, Atsushi, Cavanagh, Lois L., Tomura, Michio, Sakaue-Sawano, Asako, Kanagawa, Osami, Miyawaki, Atsushi, Hodgkin, Philip D., Weninger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346633/
https://www.ncbi.nlm.nih.gov/pubmed/25709008
http://dx.doi.org/10.1038/ncomms7301