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Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci

Multiple regulatory elements distant from their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of func...

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Detalles Bibliográficos
Autores principales:	Jäger, Roland, Migliorini, Gabriele, Henrion, Marc, Kandaswamy, Radhika, Speedy, Helen E., Heindl, Andreas, Whiffin, Nicola, Carnicer, Maria J., Broome, Laura, Dryden, Nicola, Nagano, Takashi, Schoenfelder, Stefan, Enge, Martin, Yuan, Yinyin, Taipale, Jussi, Fraser, Peter, Fletcher, Olivia, Houlston, Richard S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346635/ https://www.ncbi.nlm.nih.gov/pubmed/25695508 http://dx.doi.org/10.1038/ncomms7178

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