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Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases

Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarc...

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Detalles Bibliográficos
Autores principales: Reyes, Montserrat, Pennacchiotti, Gina, Valdes, Fabio, Montes, Rodrigo, Veloso, Marcelo, Matamala, Maria Angélica, Zanolli, Luis, Rojas-Alcayaga, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346690/
https://www.ncbi.nlm.nih.gov/pubmed/25785207
http://dx.doi.org/10.1155/2015/780856
Descripción
Sumario:Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.