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Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346690/ https://www.ncbi.nlm.nih.gov/pubmed/25785207 http://dx.doi.org/10.1155/2015/780856 |
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author | Reyes, Montserrat Pennacchiotti, Gina Valdes, Fabio Montes, Rodrigo Veloso, Marcelo Matamala, Maria Angélica Zanolli, Luis Rojas-Alcayaga, Gonzalo |
author_facet | Reyes, Montserrat Pennacchiotti, Gina Valdes, Fabio Montes, Rodrigo Veloso, Marcelo Matamala, Maria Angélica Zanolli, Luis Rojas-Alcayaga, Gonzalo |
author_sort | Reyes, Montserrat |
collection | PubMed |
description | Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis. |
format | Online Article Text |
id | pubmed-4346690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43466902015-03-17 Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases Reyes, Montserrat Pennacchiotti, Gina Valdes, Fabio Montes, Rodrigo Veloso, Marcelo Matamala, Maria Angélica Zanolli, Luis Rojas-Alcayaga, Gonzalo Case Rep Dent Case Report Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis. Hindawi Publishing Corporation 2015 2015-02-17 /pmc/articles/PMC4346690/ /pubmed/25785207 http://dx.doi.org/10.1155/2015/780856 Text en Copyright © 2015 Montserrat Reyes et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Reyes, Montserrat Pennacchiotti, Gina Valdes, Fabio Montes, Rodrigo Veloso, Marcelo Matamala, Maria Angélica Zanolli, Luis Rojas-Alcayaga, Gonzalo Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_full | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_fullStr | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_full_unstemmed | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_short | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_sort | sarcomatoid (spindle cell) carcinoma of tongue: a report of two cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346690/ https://www.ncbi.nlm.nih.gov/pubmed/25785207 http://dx.doi.org/10.1155/2015/780856 |
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