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Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases

Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarc...

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Autores principales: Reyes, Montserrat, Pennacchiotti, Gina, Valdes, Fabio, Montes, Rodrigo, Veloso, Marcelo, Matamala, Maria Angélica, Zanolli, Luis, Rojas-Alcayaga, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346690/
https://www.ncbi.nlm.nih.gov/pubmed/25785207
http://dx.doi.org/10.1155/2015/780856
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author Reyes, Montserrat
Pennacchiotti, Gina
Valdes, Fabio
Montes, Rodrigo
Veloso, Marcelo
Matamala, Maria Angélica
Zanolli, Luis
Rojas-Alcayaga, Gonzalo
author_facet Reyes, Montserrat
Pennacchiotti, Gina
Valdes, Fabio
Montes, Rodrigo
Veloso, Marcelo
Matamala, Maria Angélica
Zanolli, Luis
Rojas-Alcayaga, Gonzalo
author_sort Reyes, Montserrat
collection PubMed
description Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.
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spelling pubmed-43466902015-03-17 Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases Reyes, Montserrat Pennacchiotti, Gina Valdes, Fabio Montes, Rodrigo Veloso, Marcelo Matamala, Maria Angélica Zanolli, Luis Rojas-Alcayaga, Gonzalo Case Rep Dent Case Report Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis. Hindawi Publishing Corporation 2015 2015-02-17 /pmc/articles/PMC4346690/ /pubmed/25785207 http://dx.doi.org/10.1155/2015/780856 Text en Copyright © 2015 Montserrat Reyes et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Reyes, Montserrat
Pennacchiotti, Gina
Valdes, Fabio
Montes, Rodrigo
Veloso, Marcelo
Matamala, Maria Angélica
Zanolli, Luis
Rojas-Alcayaga, Gonzalo
Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_full Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_fullStr Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_full_unstemmed Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_short Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_sort sarcomatoid (spindle cell) carcinoma of tongue: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346690/
https://www.ncbi.nlm.nih.gov/pubmed/25785207
http://dx.doi.org/10.1155/2015/780856
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