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Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells

Reactive oxygen species (ROS) can be generated by defective endogenous reduction of oxygen by cellular enzymes or in the mitochondrial respiratory pathway, as well as by exogenous exposure to UV or environmental damaging agents. Regulation of intracellular ROS levels is critical since increases abov...

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Detalles Bibliográficos
Autores principales: Richardson, Christine, Yan, Shan, Vestal, C. Greer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346841/
https://www.ncbi.nlm.nih.gov/pubmed/25622253
http://dx.doi.org/10.3390/ijms16022366