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Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells
Reactive oxygen species (ROS) can be generated by defective endogenous reduction of oxygen by cellular enzymes or in the mitochondrial respiratory pathway, as well as by exogenous exposure to UV or environmental damaging agents. Regulation of intracellular ROS levels is critical since increases abov...
Autores principales: | Richardson, Christine, Yan, Shan, Vestal, C. Greer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346841/ https://www.ncbi.nlm.nih.gov/pubmed/25622253 http://dx.doi.org/10.3390/ijms16022366 |
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