Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines

3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh(2)Cy)Cl.

Detalles Bibliográficos
Autores principales: Su, Ji, Liu, Huixin, Hua, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346915/
https://www.ncbi.nlm.nih.gov/pubmed/25664863
http://dx.doi.org/10.3390/ijms16023599
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author Su, Ji
Liu, Huixin
Hua, Ruimao
author_facet Su, Ji
Liu, Huixin
Hua, Ruimao
author_sort Su, Ji
collection PubMed
description 3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh(2)Cy)Cl.
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spelling pubmed-43469152015-04-03 Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines Su, Ji Liu, Huixin Hua, Ruimao Int J Mol Sci Article 3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh(2)Cy)Cl. MDPI 2015-02-05 /pmc/articles/PMC4346915/ /pubmed/25664863 http://dx.doi.org/10.3390/ijms16023599 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Su, Ji
Liu, Huixin
Hua, Ruimao
Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title_full Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title_fullStr Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title_full_unstemmed Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title_short Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines
title_sort au(i)-catalyzed annulation of propargyl amine with aldehydes: one-pot cascade synthesis of 2,5-dimethylpyrazines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346915/
https://www.ncbi.nlm.nih.gov/pubmed/25664863
http://dx.doi.org/10.3390/ijms16023599
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AT liuhuixin auicatalyzedannulationofpropargylaminewithaldehydesonepotcascadesynthesisof25dimethylpyrazines
AT huaruimao auicatalyzedannulationofpropargylaminewithaldehydesonepotcascadesynthesisof25dimethylpyrazines

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