β-Hydroxybutyric Sodium Salt Inhibition of Growth Hormone and Prolactin Secretion via the cAMP/PKA/CREB and AMPK Signaling Pathways in Dairy Cow Anterior Pituitary Cells

β-hydroxybutyric acid (BHBA) regulates the synthesis and secretion of growth hormone (GH) and prolactin (PRL), but its mechanism is unknown. In this study, we detected the effects of BHBA on the activities of G protein signaling pathways, AMPK-α activity, GH, and PRL gene transcription, and GH and P...

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Detalles Bibliográficos
Autores principales: Fu, Shou-Peng, Wang, Wei, Liu, Bing-Run, Yang, Huan-Min, Ji, Hong, Yang, Zhan-Qing, Guo, Bin, Liu, Ju-Xiong, Wang, Jian-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346956/
https://www.ncbi.nlm.nih.gov/pubmed/25690038
http://dx.doi.org/10.3390/ijms16024265

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