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Metastatic Melanoma Cells Evade Immune Detection by Silencing STAT1
Transcriptional activation of major histocompatibility complex (MHC) I and II molecules by the cytokine, interferon γ (IFN-γ), is a key step in cell-mediated immunity against pathogens and tumors. Recent evidence suggests that suppression of MHC I and II expression on multiple tumor types plays impo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346960/ https://www.ncbi.nlm.nih.gov/pubmed/25690042 http://dx.doi.org/10.3390/ijms16024343 |