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Recombinant adeno-associated virus delivered human thioredoxin-PR39 prevents hypoxia-induced apoptosis of ECV304 cells☆

Human thioredoxin and antibacterial peptide, PR39, have been shown to have potent antioxidant effects that may prolong survival of cells during hypoxia. The pSSCMV/human thioredoxin-PR39 vector was successfully constructed in this study and used to infect ECV304 cells. Transfected ECV304 cells were...

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Detalles Bibliográficos
Autores principales: Ruan, Xiyun, Yuan, Zhenguo, Du, Yifeng, Yang, Guangxiao, Wang, Quanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347013/
https://www.ncbi.nlm.nih.gov/pubmed/25745468
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.09.012