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Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all ost...

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Autores principales: Lee, Yong Bin, Kim, Nam-Kyoo, Kim, Jae-Young, Kim, Hyung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Oral and Maxillofacial Surgeons 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347030/
https://www.ncbi.nlm.nih.gov/pubmed/25741469
http://dx.doi.org/10.5125/jkaoms.2015.41.1.48
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author Lee, Yong Bin
Kim, Nam-Kyoo
Kim, Jae-Young
Kim, Hyung Jun
author_facet Lee, Yong Bin
Kim, Nam-Kyoo
Kim, Jae-Young
Kim, Hyung Jun
author_sort Lee, Yong Bin
collection PubMed
description Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.
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spelling pubmed-43470302015-03-04 Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report Lee, Yong Bin Kim, Nam-Kyoo Kim, Jae-Young Kim, Hyung Jun J Korean Assoc Oral Maxillofac Surg Case Report Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning. The Korean Association of Oral and Maxillofacial Surgeons 2015-02 2015-02-24 /pmc/articles/PMC4347030/ /pubmed/25741469 http://dx.doi.org/10.5125/jkaoms.2015.41.1.48 Text en Copyright © 2015 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Yong Bin
Kim, Nam-Kyoo
Kim, Jae-Young
Kim, Hyung Jun
Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title_full Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title_fullStr Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title_full_unstemmed Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title_short Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
title_sort low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347030/
https://www.ncbi.nlm.nih.gov/pubmed/25741469
http://dx.doi.org/10.5125/jkaoms.2015.41.1.48
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