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Fluoxetine induces alkalinization of astroglial cytosol through stimulation of sodium-hydrogen exchanger 1: dissection of intracellular signaling pathways
Clinical evidence suggest astrocytic abnormality in major depression (MD) while treatment with anti-psychotic drugs affects astroglial functions. Astroglial cells are involved in pH homeostasis of the brain by transporting protons (through sodium-proton transporter 1, NHE1, glutamate transporters EA...
Autores principales: | Ren, Jienan, Song, Dan, Bai, Qiufang, Verkhratsky, Alexei, Peng, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347488/ https://www.ncbi.nlm.nih.gov/pubmed/25784857 http://dx.doi.org/10.3389/fncel.2015.00061 |
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