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TLR4 activation induces IL-1β release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung

BACKGROUND: The IL-1 family of cytokines is known to play an important role in inflammation therefore understanding the mechanism by which they are produced is paramount. Despite the recent plethora of publications dedicated to the study of these cytokines, the mechanism by which they are produced i...

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Detalles Bibliográficos
Autores principales: Eltom, Suffwan, Belvisi, Maria G, Yew-Booth, Liang, Dekkak, Bilel, Maher, Sarah A, Dubuis, Eric D, Jones, Victoria, Fitzgerald, Kate A, Birrell, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347603/
https://www.ncbi.nlm.nih.gov/pubmed/25085021
http://dx.doi.org/10.1186/s12931-014-0087-0

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