Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

Mouse embryonic stem cells (ESCs) are genetically more stable than somatic cells, thereby preventing the passage of genomic abnormalities to their derivatives including germ cells. The underlying mechanisms, however, remain largely unclear. In this paper, we show that the stemness factor Sall4 is re...

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Detalles Bibliográficos
Autores principales: Xiong, Jianhua, Todorova, Dilyana, Su, Ning-Yuan, Kim, Jinchul, Lee, Pei-Jen, Shen, Zhouxin, Briggs, Steven P., Xu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347641/
https://www.ncbi.nlm.nih.gov/pubmed/25733712
http://dx.doi.org/10.1083/jcb.201408106

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