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Concomitant downregulation of the imprinted genes DLK1 and MEG3 at 14q32.2 by epigenetic mechanisms in urothelial carcinoma

BACKGROUND: The two oppositely imprinted and expressed genes, DLK1 and MEG3, are located in the same gene cluster at 14q32. Previous studies in bladder cancer have suggested that tumor suppressor genes are located in this region, but these have not been identified. RESULTS: We observed that both DLK...

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Detalles Bibliográficos
Autores principales:	Greife, Annemarie, Knievel, Judith, Ribarska, Teodora, Niegisch, Günter, Schulz, Wolfgang A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348104/ https://www.ncbi.nlm.nih.gov/pubmed/25741387 http://dx.doi.org/10.1186/1868-7083-6-29

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