CRISPR/Cas9 and TALE: beyond cut and paste

Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Liping, Ren, Ruotong, Wu, Jun, Suzuki, Keiichiro, Izpisua Belmote, Juan Carlos, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348244/
https://www.ncbi.nlm.nih.gov/pubmed/25722052
http://dx.doi.org/10.1007/s13238-015-0137-5
_version_ 1782359905623080960
author Deng, Liping
Ren, Ruotong
Wu, Jun
Suzuki, Keiichiro
Izpisua Belmote, Juan Carlos
Liu, Guang-Hui
author_facet Deng, Liping
Ren, Ruotong
Wu, Jun
Suzuki, Keiichiro
Izpisua Belmote, Juan Carlos
Liu, Guang-Hui
author_sort Deng, Liping
collection PubMed
description Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.
format Online
Article
Text
id pubmed-4348244
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Higher Education Press
record_format MEDLINE/PubMed
spelling pubmed-43482442015-03-05 CRISPR/Cas9 and TALE: beyond cut and paste Deng, Liping Ren, Ruotong Wu, Jun Suzuki, Keiichiro Izpisua Belmote, Juan Carlos Liu, Guang-Hui Protein Cell Perspective Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions. Higher Education Press 2015-02-27 2015-03 /pmc/articles/PMC4348244/ /pubmed/25722052 http://dx.doi.org/10.1007/s13238-015-0137-5 Text en © The Author(s) 2015 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Perspective
Deng, Liping
Ren, Ruotong
Wu, Jun
Suzuki, Keiichiro
Izpisua Belmote, Juan Carlos
Liu, Guang-Hui
CRISPR/Cas9 and TALE: beyond cut and paste
title CRISPR/Cas9 and TALE: beyond cut and paste
title_full CRISPR/Cas9 and TALE: beyond cut and paste
title_fullStr CRISPR/Cas9 and TALE: beyond cut and paste
title_full_unstemmed CRISPR/Cas9 and TALE: beyond cut and paste
title_short CRISPR/Cas9 and TALE: beyond cut and paste
title_sort crispr/cas9 and tale: beyond cut and paste
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348244/
https://www.ncbi.nlm.nih.gov/pubmed/25722052
http://dx.doi.org/10.1007/s13238-015-0137-5
work_keys_str_mv AT dengliping crisprcas9andtalebeyondcutandpaste
AT renruotong crisprcas9andtalebeyondcutandpaste
AT wujun crisprcas9andtalebeyondcutandpaste
AT suzukikeiichiro crisprcas9andtalebeyondcutandpaste
AT izpisuabelmotejuancarlos crisprcas9andtalebeyondcutandpaste
AT liuguanghui crisprcas9andtalebeyondcutandpaste

Ejemplares similares