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CRISPR/Cas9 and TALE: beyond cut and paste
Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal...
Autores principales: | Deng, Liping, Ren, Ruotong, Wu, Jun, Suzuki, Keiichiro, Izpisua Belmote, Juan Carlos, Liu, Guang-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348244/ https://www.ncbi.nlm.nih.gov/pubmed/25722052 http://dx.doi.org/10.1007/s13238-015-0137-5 |
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