YY1 suppresses FEN1 over-expression and drug resistance in breast cancer

BACKGROUND: Drug resistance is a major challenge in cancer therapeutics. Abundant evidence indicates that DNA repair systems are enhanced after repetitive chemotherapeutic treatments, rendering cancers cells drug-resistant. Flap endonuclease 1 (FEN1) plays critical roles in DNA replication and repai...

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Detalles Bibliográficos
Autores principales: Wang, Jianwei, Zhou, Lina, Li, Zhi, Zhang, Ting, Liu, Wenpeng, Liu, Zheng, Yuan, Yate-Ching, Su, Fan, Xu, Lu, Wang, Yan, Zhou, Xiaotong, Xu, Hong, Hua, Yuejin, Wang, Ying-Jie, Zheng, Li, Teng, Yue-E, Shen, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348373/
https://www.ncbi.nlm.nih.gov/pubmed/25885449
http://dx.doi.org/10.1186/s12885-015-1043-1

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