From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)

We report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bi...

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Autores principales: Gabriel, Marta F., González-Delgado, Purificación, Postigo, Idoia, Fernández, Javier, Soriano, Victor, Cueva, Begoña, Martínez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348448/
https://www.ncbi.nlm.nih.gov/pubmed/25750856
http://dx.doi.org/10.1016/j.mmcr.2015.02.003
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author Gabriel, Marta F.
González-Delgado, Purificación
Postigo, Idoia
Fernández, Javier
Soriano, Victor
Cueva, Begoña
Martínez, Jorge
author_facet Gabriel, Marta F.
González-Delgado, Purificación
Postigo, Idoia
Fernández, Javier
Soriano, Victor
Cueva, Begoña
Martínez, Jorge
author_sort Gabriel, Marta F.
collection PubMed
description We report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bisporus mushroom were identified as patient-specific IgE-binding proteins. Cross-reactivity between A. bisporus MnSOD and mold aeroallergens was confirmed. We conclude that prior sensitization to mold aeroallergens might explain severe food reactions to cross-reacting homologs mushroom proteins.
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spelling pubmed-43484482015-03-07 From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus) Gabriel, Marta F. González-Delgado, Purificación Postigo, Idoia Fernández, Javier Soriano, Victor Cueva, Begoña Martínez, Jorge Med Mycol Case Rep Case Report We report a case of a 38-year-old mold-allergic patient who developed episodes of generalized urticaria and systemic anaphylactic shock immediately after ingesting button mushrooms. A manganese-dependent superoxide dismutase (MnSOD) and a NADP-dependent mannitol dehydrogenase (MtDH) from Agaricus bisporus mushroom were identified as patient-specific IgE-binding proteins. Cross-reactivity between A. bisporus MnSOD and mold aeroallergens was confirmed. We conclude that prior sensitization to mold aeroallergens might explain severe food reactions to cross-reacting homologs mushroom proteins. Elsevier 2015-02-24 /pmc/articles/PMC4348448/ /pubmed/25750856 http://dx.doi.org/10.1016/j.mmcr.2015.02.003 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Case Report
Gabriel, Marta F.
González-Delgado, Purificación
Postigo, Idoia
Fernández, Javier
Soriano, Victor
Cueva, Begoña
Martínez, Jorge
From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_full From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_fullStr From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_full_unstemmed From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_short From respiratory sensitization to food allergy: Anaphylactic reaction after ingestion of mushrooms (Agaricus bisporus)
title_sort from respiratory sensitization to food allergy: anaphylactic reaction after ingestion of mushrooms (agaricus bisporus)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348448/
https://www.ncbi.nlm.nih.gov/pubmed/25750856
http://dx.doi.org/10.1016/j.mmcr.2015.02.003
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