Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient

We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its cl...

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Autores principales: Salzer, Helmut J.F., Rolling, Thierry, Klupp, Eva-Maria, Schmiedel, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348452/
https://www.ncbi.nlm.nih.gov/pubmed/25750857
http://dx.doi.org/10.1016/j.mmcr.2015.02.001
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author Salzer, Helmut J.F.
Rolling, Thierry
Klupp, Eva-Maria
Schmiedel, Stefan
author_facet Salzer, Helmut J.F.
Rolling, Thierry
Klupp, Eva-Maria
Schmiedel, Stefan
author_sort Salzer, Helmut J.F.
collection PubMed
description We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its closest known relative Candida albicans, reports of severe fungal infections are increasing. This case indicates that the pathogenicity of C. dubliniensis may be higher than previously believed. Therefore fungal infections caused by this dimorph fungus should be kept in mind in immunocompromised patients with spondylodiscitis and spinal abscess.
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spelling pubmed-43484522015-03-07 Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient Salzer, Helmut J.F. Rolling, Thierry Klupp, Eva-Maria Schmiedel, Stefan Med Mycol Case Rep Article We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its closest known relative Candida albicans, reports of severe fungal infections are increasing. This case indicates that the pathogenicity of C. dubliniensis may be higher than previously believed. Therefore fungal infections caused by this dimorph fungus should be kept in mind in immunocompromised patients with spondylodiscitis and spinal abscess. Elsevier 2015-02-24 /pmc/articles/PMC4348452/ /pubmed/25750857 http://dx.doi.org/10.1016/j.mmcr.2015.02.001 Text en © 2015 Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Salzer, Helmut J.F.
Rolling, Thierry
Klupp, Eva-Maria
Schmiedel, Stefan
Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_full Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_fullStr Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_full_unstemmed Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_short Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_sort hematogenous dissemination of candida dubliniensis causing spondylodiscitis and spinal abscess in a hiv-1 and hcv-coinfected patient
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348452/
https://www.ncbi.nlm.nih.gov/pubmed/25750857
http://dx.doi.org/10.1016/j.mmcr.2015.02.001
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