Patient-Specific Modeling of Regional Antibiotic Concentration Levels in Airways of Patients with Cystic Fibrosis: Are We Dosing High Enough?

BACKGROUND: Pseudomonas aeruginosa (Pa) infection is an important contributor to the progression of cystic fibrosis (CF) lung disease. The cornerstone treatment for Pa infection is the use of inhaled antibiotics. However, there is substantial lung disease heterogeneity within and between patients th...

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Detalles Bibliográficos
Autores principales: Bos, Aukje C., van Holsbeke, Cedric, de Backer, Jan W., van Westreenen, Mireille, Janssens, Hettie M., Vos, Wim G., Tiddens, Harm A. W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348481/
https://www.ncbi.nlm.nih.gov/pubmed/25734630
http://dx.doi.org/10.1371/journal.pone.0118454

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