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Discovery of Novel New Delhi Metallo-β-Lactamases-1 Inhibitors by Multistep Virtual Screening

The emergence of NDM-1 containing multi-antibiotic resistant "Superbugs" necessitates the needs of developing of novel NDM-1inhibitors. In this study, we report the discovery of novel NDM-1 inhibitors by multi-step virtual screening. From a 2,800,000 virtual drug-like compound library sele...

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Detalles Bibliográficos
Autores principales:	Wang, Xuequan, Lu, Meiling, Shi, Yang, Ou, Yu, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348537/ https://www.ncbi.nlm.nih.gov/pubmed/25734558 http://dx.doi.org/10.1371/journal.pone.0118290

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