Cargando…

HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation

Cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol esters (CE) from atheroprotective high-density lipoproteins (HDL) to atherogenic low-density lipoproteins (LDL). CETP inhibition has been regarded as a promising strategy for increasing HDL levels and subsequently reducin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Meng, Charles, River, Tong, Huimin, Zhang, Lei, Patel, Mili, Wang, Francis, Rames, Matthew J., Ren, Amy, Rye, Kerry-Anne, Qiu, Xiayang, Johns, Douglas G., Charles, M. Arthur, Ren, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348656/
https://www.ncbi.nlm.nih.gov/pubmed/25737239
http://dx.doi.org/10.1038/srep08741

Ejemplares similares