Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity

BACKGROUND: Inhalation of benzene at levels below the current exposure limit values leads to hematotoxicity in occupationally exposed workers. OBJECTIVE: We sought to evaluate Diversity Outbred (DO) mice as a tool for exposure threshold assessment and to identify genetic factors that influence benze...

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Detalles Bibliográficos
Autores principales: French, John E., Gatti, Daniel M., Morgan, Daniel L., Kissling, Grace E., Shockley, Keith R., Knudsen, Gabriel A., Shepard, Kim G., Price, Herman C., King, Deborah, Witt, Kristine L., Pedersen, Lars C., Munger, Steven C., Svenson, Karen L., Churchill, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348743/
https://www.ncbi.nlm.nih.gov/pubmed/25376053
http://dx.doi.org/10.1289/ehp.1408202

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