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The gap junction blocker carbenoxolone enhances propofol and sevoflurane-induced loss of consciousness☆

General anesthetics induce loss of consciousness by inhibiting ascending arousal pathways, and they interfere with gap junction electrical coupling. The present study aimed to determine whether inhibition of gap junction-mediated signaling could influence general anesthetic-induced loss of conscious...

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Detalles Bibliográficos
Autores principales: Liu, Zhigang, Liu, Yongfang, Zhao, Bo, Du, Li, Xia, Zhongyuan, Chen, Xiangdong, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348993/
https://www.ncbi.nlm.nih.gov/pubmed/25745433
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.07.002