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Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
The amino acid sequence of a protein affects both its structure and its function. Thus, the ability to modify the sequence, and hence the structure and activity, of individual proteins in a systematic way, opens up many opportunities, both scientifically and (as we focus on here) for exploitation in...
Autores principales: | Currin, Andrew, Swainston, Neil, Day, Philip J., Kell, Douglas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349129/ https://www.ncbi.nlm.nih.gov/pubmed/25503938 http://dx.doi.org/10.1039/c4cs00351a |
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