MicroRNA-122: A Novel Hepatocyte-Enriched in vitro Marker of Drug-Induced Cellular Toxicity

Emerging hepatic models for the study of drug-induced toxicity include pluripotent stem cell-derived hepatocyte-like cells (HLCs) and complex hepatocyte-non-parenchymal cellular coculture to mimic the complex multicellular interactions that recapitulate the niche environment in the human liver. Howe...

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Detalles Bibliográficos
Autores principales: Kia, Richard, Kelly, Lorna, Sison-Young, Rowena L. C., Zhang, Fang, Pridgeon, Chris S., Heslop, James A., Metcalfe, Pete, Kitteringham, Neil R., Baxter, Melissa, Harrison, Sean, Hanley, Neil A., Burke, Zoë D., Storm, Mike P., Welham, Melanie J., Tosh, David, Küppers-Munther, Barbara, Edsbagge, Josefina, Starkey Lewis, Philip J., Bonner, Frank, Harpur, Ernie, Sidaway, James, Bowes, Joanne, Fenwick, Stephen W., Malik, Hassan, Goldring, Chris E. P., Park, B. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
MicroRNA-122 as A Biomarker of Liver Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349141/
https://www.ncbi.nlm.nih.gov/pubmed/25527335
http://dx.doi.org/10.1093/toxsci/kfu269

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