Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

Brain glycogen synthase kinase-3 (GSK3) is hyperactive in several neurological conditions that involve impairments in both cognition and neurogenesis. This raises the hypotheses that hyperactive GSK3 may directly contribute to impaired cognition, and that this may be related to deficiencies in neura...

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Detalles Bibliográficos
Autores principales: Pardo, Marta, King, Margaret K., Perez-Costas, Emma, Melendez-Ferro, Miguel, Martinez, Ana, Beurel, Eleonore, Jope, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349180/
https://www.ncbi.nlm.nih.gov/pubmed/25788881
http://dx.doi.org/10.3389/fnbeh.2015.00055

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