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NKG2D Ligands in Tumor Immunity: Two Sides of a Coin

The activating/co-stimulatory receptor NKG2D (natural-killer group 2, member D) is expressed on the surface of all human NK, NKT, CD8(+) T, and subsets of γδ(+) T cells. The significance of NKG2D function in tumor immunity has been well demonstrated in experimental animal models. However, the role o...

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Detalles Bibliográficos
Autores principales: Zhang, Jinyu, Basher, Fahmin, Wu, Jennifer D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349182/
https://www.ncbi.nlm.nih.gov/pubmed/25788898
http://dx.doi.org/10.3389/fimmu.2015.00097