The Integrator complex controls the termination of transcription at diverse classes of gene targets

Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical function remained unknown. Using affinity purifications and HIV Integration targeting-sequencing (HIT-Seq), we find that these complexes are part of the Integrator complex...

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Detalles Bibliográficos
Autores principales: Skaar, Jeffrey R, Ferris, Andrea L, Wu, Xiaolin, Saraf, Anita, Khanna, Kum Kum, Florens, Laurence, Washburn, Michael P, Hughes, Stephen H, Pagano, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349240/
https://www.ncbi.nlm.nih.gov/pubmed/25675981
http://dx.doi.org/10.1038/cr.2015.19

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