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B-cell activating factor in the pathophysiology of multiple myeloma: a target for therapy?
Multiple myeloma (MM) is a currently incurable malignancy of plasma cells. Malignant myeloma cells (MMCs) are heavily dependent upon the bone marrow (BM) microenvironment for their survival. One component of this tumor microenvironment, B-Cell Activating Factor (BAFF), has been implicated as a key p...
Autores principales: | Hengeveld, P J, Kersten, M J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349256/ https://www.ncbi.nlm.nih.gov/pubmed/25723853 http://dx.doi.org/10.1038/bcj.2015.3 |
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