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Zn(2+) reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder

Our laboratory recently characterized a novel autism spectrum disorder (ASD)-associated de novo missense mutation in the human dopamine transporter (hDAT) gene SLC6A3 (hDAT T356M). This hDAT variant exhibits dysfunctional forward and reverse transport properties that may contribute to DA dysfunction...

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Detalles Bibliográficos
Autores principales:	Hamilton, Peter J, Shekar, Aparna, Belovich, Andrea N, Christianson, Nicole Bibus, Campbell, Nicholas G, Sutcliffe, James S, Galli, Aurelio, Matthies, Heinrich JG, Erreger, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349303/ https://www.ncbi.nlm.nih.gov/pubmed/25741436 http://dx.doi.org/10.1186/s13229-015-0002-7

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