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Automated genomic context analysis and experimental validation platform for discovery of prokaryote transcriptional regulator functions

BACKGROUND: The clustering of genes in a pathway and the co-location of functionally related genes is widely recognized in prokaryotes. We used these characteristics to predict the metabolic involvement for a Transcriptional Regulator (TR) of unknown function, identified and confirmed its biological...

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Detalles Bibliográficos
Autores principales: Martí-Arbona, Ricardo, Mu, Fangping, Nowak-Lovato, Kristy L, Wren, Melinda S, Unkefer, Clifford J, Unkefer, Pat J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349456/
https://www.ncbi.nlm.nih.gov/pubmed/25523622
http://dx.doi.org/10.1186/1471-2164-15-1142