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Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells
The acquisition of cell motility is an early step in melanoma metastasis. Here we use intravital imaging of signalling reporter cell-lines combined with genome-wide transcriptional analysis to define signalling pathways and genes associated with melanoma metastasis. Intravital imaging revealed heter...
Autores principales: | Manning, Cerys S, Hooper, Steven, Sahai, Erik A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349503/ https://www.ncbi.nlm.nih.gov/pubmed/25381824 http://dx.doi.org/10.1038/onc.2014.362 |
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