Metabolic Effects of Cholecystectomy: Gallbladder Ablation Increases Basal Metabolic Rate through G-Protein Coupled Bile Acid Receptor Gpbar1-Dependent Mechanisms in Mice

BACKGROUND & AIMS: Bile acids (BAs) regulate energy expenditure by activating G-protein Coupled Bile Acid Receptor Gpbar1/TGR5 by cAMP-dependent mechanisms. Cholecystectomy (XGB) increases BAs recirculation rates resulting in increased tissue exposure to BAs during the light phase of the diurnal...

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Detalles Bibliográficos
Autores principales: Cortés, Víctor, Amigo, Ludwig, Zanlungo, Silvana, Galgani, José, Robledo, Fermín, Arrese, Marco, Bozinovic, Francisco, Nervi, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349594/
https://www.ncbi.nlm.nih.gov/pubmed/25738495
http://dx.doi.org/10.1371/journal.pone.0118478

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