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miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that recognize sites of complementarity of target messenger RNAs, resulting in transcriptional regulation and translational repression of target genes. In Huntington’s disease (HD), a neurodegenerative disease caused by a trinucleotide repeat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349621/ https://www.ncbi.nlm.nih.gov/pubmed/25889241 http://dx.doi.org/10.1186/s12920-015-0083-3 |