miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that recognize sites of complementarity of target messenger RNAs, resulting in transcriptional regulation and translational repression of target genes. In Huntington’s disease (HD), a neurodegenerative disease caused by a trinucleotide repeat...

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Detalles Bibliográficos
Autores principales: Hoss, Andrew G, Labadorf, Adam, Latourelle, Jeanne C, Kartha, Vinay K, Hadzi, Tiffany C, Gusella, James F, MacDonald, Marcy E, Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Vonsattel, Jean Paul, Myers, Richard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349621/
https://www.ncbi.nlm.nih.gov/pubmed/25889241
http://dx.doi.org/10.1186/s12920-015-0083-3

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