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Deguelin induces the apoptosis of lung cancer cells through regulating a ROS driven Akt pathway

BACKGROUND: Duguelin is a rotenoid extracted from plants and has potent antitumor effects in vitro and in vivo. However, the mechanism underlying the antitumor effect remains unclear. Our preliminary study showed that Deguelin is effective to stimulate the generation of Reactive Oxygen Species (ROS)...

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Detalles Bibliográficos
Autores principales:	Xu, Huae, Li, Xiaolin, Ding, Wenqiu, Zeng, Xiaoning, Kong, Hui, Wang, Hong, Xie, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349657/ https://www.ncbi.nlm.nih.gov/pubmed/25741219 http://dx.doi.org/10.1186/s12935-015-0166-4

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