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Modified Vaccinia virus Ankara but not vaccinia virus induces chemokine expression in cells of the monocyte/macrophage lineage

BACKGROUND: The orthopoxvirus strain Modified Vaccinia virus Ankara (MVA) rapidly induces innate immune responses. Previously, we demonstrated that CCL2 and CCR1 are important players in MVA induced recruitment of leukocytes to the lung. Alveolar macrophages are sentinel cells in the lung, which are...

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Detalles Bibliográficos
Autores principales: Lehmann, Michael H, Price, Philip JR, Brandmüller, Christine, Sutter, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349667/
https://www.ncbi.nlm.nih.gov/pubmed/25889495
http://dx.doi.org/10.1186/s12985-015-0252-1

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