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Improving the large scale purification of the HIV microbicide, griffithsin

BACKGROUND: Griffithsin is a broad spectrum antiviral lectin that inhibits viral entry and maturation processes through binding clusters of oligomannose glycans on viral envelope glycoproteins. An efficient, scaleable manufacturing process for griffithsin active pharmaceutical ingredient (API) is es...

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Detalles Bibliográficos
Autores principales:	Fuqua, Joshua L, Wanga, Valentine, Palmer, Kenneth E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349730/ https://www.ncbi.nlm.nih.gov/pubmed/25887919 http://dx.doi.org/10.1186/s12896-015-0120-5

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