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Alterations of BDNF and trkB mRNA Expression in the 6-Hydroxydopamine-Induced Model of Preclinical Stages of Parkinson’s Disease: An Influence of Chronic Pramipexole in Rats

Our recent study has indicated that a moderate lesion of the mesostriatal and mesolimbic pathways in rats, modelling preclinical stages of Parkinson’s disease, induces a depressive-like behaviour which is reversed by chronic treatment with pramipexole. The purpose of the present study was to examine...

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Detalles Bibliográficos
Autores principales: Berghauzen-Maciejewska, Klemencja, Wardas, Jadwiga, Kosmowska, Barbara, Głowacka, Urszula, Kuter, Katarzyna, Ossowska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349741/
https://www.ncbi.nlm.nih.gov/pubmed/25739024
http://dx.doi.org/10.1371/journal.pone.0117698

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