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PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation

PDZ binding-kinase (PBK) (also named T-lymphokine-activated killer cell-originated protein kinase (TOPK)), a serine/threonine kinase, is tightly controlled in normal tissues but elevated in many tumors, and functions in tumorigenesis and metastasis. However, the signaling that regulates expression o...

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Detalles Bibliográficos
Autores principales:	Dou, Xiaoyan, Wei, Jing, Sun, Aiqin, Shao, Genbao, Childress, Chandra, Yang, Wannian, Lin, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349756/ https://www.ncbi.nlm.nih.gov/pubmed/25745361 http://dx.doi.org/10.1186/s12935-015-0178-0

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