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Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53(R270H/+)WAPCre mouse model

INTRODUCTION: Insulin analogues are structurally modified molecules with altered pharmaco-kinetic and -dynamic properties compared to regular human insulin used by diabetic patients. While these compounds are tested for undesired mitogenic effects, an epidemiological discussion is ongoing regarding...

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Detalles Bibliográficos
Autores principales:	ter Braak, Bas, Siezen, Christine, Speksnijder, Ewoud N, Koedoot, Esmee, van Steeg, Harry, Salvatori, Daniela CF, van de Water, Bob, van der Laan, Jan Willem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349771/ https://www.ncbi.nlm.nih.gov/pubmed/25848982 http://dx.doi.org/10.1186/s13058-015-0518-y

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