Cargando…
A Specific Nuclear DNA Background Is Required for High Frequency Lymphoma Development in Transmitochondrial Mice with G13997A mtDNA
We previously found that mouse mitochondrial DNA (mtDNA) with a G13997A mutation (G13997A mtDNA) controls not only the transformation of cultured lung carcinoma cells from poorly metastatic into highly metastatic cells, but also the transformation of lymphocytes into lymphomas in living C57BL/6 (B6)...
Autores principales: | Hashizume, Osamu, Yamanashi, Haruka, Taketo, Makoto M., Nakada, Kazuto, Hayashi, Jun-Ichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349826/ https://www.ncbi.nlm.nih.gov/pubmed/25738506 http://dx.doi.org/10.1371/journal.pone.0118561 |
Ejemplares similares
-
Administration of an Antioxidant Prevents Lymphoma Development in
Transmitochondrial Mice Overproducing Reactive Oxygen Species
por: Yamanashi, Haruka, et al.
Publicado: (2014) -
Selection of Rodent Species Appropriate for mtDNA Transfer to Generate
Transmitochondrial Mito-Mice Expressing Mitochondrial Respiration Defects
por: Enoki, Shunkei, et al.
Publicado: (2014) -
Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants
por: Pye, Deborah, et al.
Publicado: (2006) -
Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation
por: Kirby, D. M. , et al.
Publicado: (2009) -
Human Retinal Transmitochondrial Cybrids with J or H mtDNA Haplogroups Respond Differently to Ultraviolet Radiation: Implications for Retinal Diseases
por: Malik, Deepika, et al.
Publicado: (2014)