Cargando…

Interaction between the Type III Effector VopO and GEF-H1 Activates the RhoA-ROCK Pathway

Vibrio parahaemolyticus is an important pathogen that causes food-borne gastroenteritis in humans. The type III secretion system encoded on chromosome 2 (T3SS2) plays a critical role in the enterotoxic activity of V. parahaemolyticus. Previous studies have demonstrated that T3SS2 induces actin stres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hiyoshi, Hirotaka, Okada, Ryu, Matsuda, Shigeaki, Gotoh, Kazuyoshi, Akeda, Yukihiro, Iida, Tetsuya, Kodama, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349864/ https://www.ncbi.nlm.nih.gov/pubmed/25738744 http://dx.doi.org/10.1371/journal.ppat.1004694

Ejemplares similares

Vibrio parahaemolyticus Senses Intracellular K(+) To Translocate Type III Secretion System 2 Effectors Effectively
por: Tandhavanant, Sarunporn, et al.
Publicado: (2018)

Bile Acid-Induced Virulence Gene Expression of Vibrio parahaemolyticus Reveals a Novel Therapeutic Potential for Bile Acid Sequestrants
por: Gotoh, Kazuyoshi, et al.
Publicado: (2010)

Pointed-end processive elongation of actin filaments by Vibrio effectors VopF and VopL
por: Kudryashova, Elena, et al.
Publicado: (2022)

Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF
por: Scott, David W., et al.
Publicado: (2016)

Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF
por: Yoshida, Tatsushi, et al.
Publicado: (2016)

Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK
por: Salinas, Romina P., et al.
Publicado: (2015)

Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization
por: van Unen, Jakobus, et al.
Publicado: (2015)

p115RhoGEF activates RhoA to support tight junction maintenance and remodeling
por: Chumki, Shahana A., et al.
Publicado: (2022)

Two Regulators of Vibrio parahaemolyticus Play Important Roles in Enterotoxicity by Controlling the Expression of Genes in the Vp-PAI Region
por: Kodama, Toshio, et al.
Publicado: (2010)

Mechanism of Actin Filament Nucleation by the Bacterial Effector VopL
por: Yu, Bingke, et al.
Publicado: (2011)

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF
por: Zheng, Meiying, et al.
Publicado: (2009)

Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA
por: Wang, Junyi, et al.
Publicado: (2021)

Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase
por: Chen, Zhe, et al.
Publicado: (2018)

Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells
por: Eitaki, Masato, et al.
Publicado: (2012)

Spatially restricted activation of RhoA at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis
por: Terry, Stephen J., et al.
Publicado: (2011)

Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells
por: Perry, Nicole A., et al.
Publicado: (2014)

A TRANSCRIPTIONAL CROSS–TALK BETWEEN RhoA AND c–Myc INHIBITS THE RhoA/Rock–DEPENDENT CYTOSKELETON
por: Sauzeau, Vincent, et al.
Publicado: (2010)

Regulation and functions of the RhoA regulatory guanine nucleotide exchange factor GEF-H1
por: Joo, Emily, et al.
Publicado: (2020)

The RhoA-ROCK pathway in the regulation of T and B cell responses
por: Ricker, Edd, et al.
Publicado: (2016)

RhoA, ROCK-1, and ROCK-2 Gene Expression and Polymorphisms in Cholesteatoma Patients
por: Görür, Kemal, et al.
Publicado: (2021)

Plexin-B1/RhoGEF–mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
por: Swiercz, Jakub M., et al.
Publicado: (2004)

Modulating RhoA effectors induces transitions to oscillatory and more wavelike RhoA dynamics in Caenorhabditis elegans zygotes
por: Yao, Baixue, et al.
Publicado: (2022)

The bacterial virulence factors VopL and VopF nucleate actin from the pointed end
por: Burke, Thomas A., et al.
Publicado: (2017)

PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells
por: Wong, Kit, et al.
Publicado: (2007)

The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1
por: Dubash, Adi D., et al.
Publicado: (2013)

RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration
por: Olson, Hannah M., et al.
Publicado: (2023)

Axon growth inhibition by RhoA/ROCK in the central nervous system
por: Fujita, Yuki, et al.
Publicado: (2014)

Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions
por: Han, Jiayin, et al.
Publicado: (2016)

RhoA and RhoC Are Both Required for the ROCK II-Dependent Promotion of Centrosome Duplication
por: Kanai, Masayuki, et al.
Publicado: (2010)

ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements
por: Seccia, Teresa M., et al.
Publicado: (2020)

Electrochemical Performance of Nanosized Disordered LiVOPO(4)
por: Shi, Yong, et al.
Publicado: (2018)

Rgnef (p190RhoGEF) Knockout Inhibits RhoA Activity, Focal Adhesion Establishment, and Cell Motility Downstream of Integrins
por: Miller, Nichol L. G., et al.
Publicado: (2012)

MyoGEF regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC
por: Wu, Di, et al.
Publicado: (2009)

Vav3, a GEF for RhoA, Plays a Critical Role under High Glucose Conditions
por: Sha, Jie, et al.
Publicado: (2014)

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA
por: Jiu, Yaming, et al.
Publicado: (2017)

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles
por: Shan, Shidong, et al.
Publicado: (2023)

GEF-effector interactions
por: Jackson, Catherine L
Publicado: (2014)

A Cytotoxic Type III Secretion Effector of Vibrio parahaemolyticus Targets Vacuolar H(+)-ATPase Subunit c and Ruptures Host Cell Lysosomes
por: Matsuda, Shigeaki, et al.
Publicado: (2012)

The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
por: Glotfelty, Elliot J., et al.
Publicado: (2023)

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock
por: Mikelis, Constantinos M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9ulu54gvhn34lmicqsut6alsvd