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YSY01A, a Novel Proteasome Inhibitor, Induces Cell Cycle Arrest on G2 Phase in MCF-7 Cells via ERα and PI3K/Akt Pathways

Given that the proteasome is essential for multiple cellular processes by degrading diverse regulatory proteins, inhibition of the proteasome has emerged as an attractive target for anti-cancer therapy. YSY01A is a novel small molecule compound targeting the proteasome. The compound was found to sup...

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Detalles Bibliográficos
Autores principales:	Xue, Bingjie, Huang, Wei, Yuan, Xia, Xu, Bo, Lou, Yaxin, Zhou, Quan, Ran, Fuxiang, Ge, Zemei, Li, Runtao, Cui, Jingrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349871/ https://www.ncbi.nlm.nih.gov/pubmed/25767601 http://dx.doi.org/10.7150/jca.10733

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