Clinicopathologic Significance of BRAF Mutation and Extracellular Signal Regulated Kinase 1/2 Expression in Patients With a Colorectal Adenocarcinoma

PURPOSE: BRAF mutation and expression of extracellular signal regulated kinase (ERK) are linked with colorectal carcinogenesis through the serrated pathway. BRAF and ERK1/2 play important roles in the activation of mitogen-activated protein (MAP) kinase signaling pathways. The present study investig...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Ook, Kim, Beom Gyu, Cha, Seong Jae, Park, Yong Gum, Lee, Tae Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Coloproctology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349919/
https://www.ncbi.nlm.nih.gov/pubmed/25745621
http://dx.doi.org/10.3393/ac.2015.31.1.9

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