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Identification of Ellagic acid analogues as potent inhibitor of protein Kinase CK2:A chemopreventive role in oral Cancer

Over expression of Protein kinase (CK2) suppresses apoptosis induced by a variety of agents, whereas down-regulation of CK2 sensitizes cells to induction of apoptosis. In this study, we have built quantitative structure activity relationship (QSAR) models, which were trained and tested on experiment...

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Detalles Bibliográficos
Autores principales: Srivastava, Rashi, Akthar, Salman, Sharma, Rolee, Mishra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349935/
https://www.ncbi.nlm.nih.gov/pubmed/25780276
http://dx.doi.org/10.6026/97320630011021