Cargando…

[(18)F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents

PURPOSE: The adenosine A(3) receptor (A3R) is involved in cardiovascular, neurological and tumour-related pathologies and serves as an exceptional pharmaceutical target in the clinical setting. A3R antagonists are considered antiinflammatory, antiallergic and anticancer agents, and to have potential...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haeusler, Daniela, Kuntner, Claudia, Nics, Lukas, Savli, Markus, Zeilinger, Markus, Wanek, Thomas, Karagiannis, Panagiotis, Lanzenberger, Rupert R., Langer, Oliver, Shanab, Karem, Spreitzer, Helmut, Wadsak, Wolfgang, Hacker, Marcus, Mitterhauser, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349960/ https://www.ncbi.nlm.nih.gov/pubmed/25601336 http://dx.doi.org/10.1007/s00259-014-2976-3

Ejemplares similares

[(18)F]FE@SNAP—a specific PET tracer for melanin-concentrating hormone receptor 1 imaging?
por: Philippe, Cécile, et al.
Publicado: (2016)

[(18)F]FE@SNAP—A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): Microfluidic and vessel-based approaches
por: Philippe, Cécile, et al.
Publicado: (2012)

Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)
por: Philippe, Cécile, et al.
Publicado: (2013)

New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics
por: Zeilinger, Markus, et al.
Publicado: (2017)

A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer
por: Shanab, Karem, et al.
Publicado: (2014)

SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [(18)F]FE@SNAP and [(11)C]SNAP-7941
por: Philippe, Cécile, et al.
Publicado: (2018)

Preclinical In Vitro and In Vivo Evaluation of [(18)F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer
por: Balber, T., et al.
Publicado: (2018)

Syntheses of Precursors and Reference Compounds of the Melanin-Concentrating Hormone Receptor 1 (MCHR1) Tracers [(11)C]SNAP-7941 and [(18)F]FE@SNAP for Positron Emission Tomography
por: Schirmer, Eva, et al.
Publicado: (2013)

In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [(11)C]SNAP-7941 and [(18)F]FE@SNAP reveal specific uptake in the ventricular system
por: Zeilinger, Markus, et al.
Publicado: (2017)

Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor
por: Haeusler, D., et al.
Publicado: (2015)

High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People
por: Kranz, Georg S., et al.
Publicado: (2015)

Radiosynthesis of [(11)C]SNAP-7941—the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1)
por: Philippe, C., et al.
Publicado: (2012)

Reliable set-up for in-loop (11)C-carboxylations using Grignard reactions for the preparation of [carbonyl-(11)C]WAY-100635 and [(11)C]-(+)-PHNO()
por: Rami-Mark, Christina, et al.
Publicado: (2013)

Comparison of fully-automated radiosyntheses of [(11)C]erlotinib for preclinical and clinical use starting from in target produced [(11)C]CO(2) or [(11)C]CH(4)
por: Philippe, Cécile, et al.
Publicado: (2018)

[(18)F]FMeNER-D2: Reliable fully-automated synthesis for visualization of the norepinephrine transporter
por: Rami-Mark, Christina, et al.
Publicado: (2013)

Parameter evaluation and fully-automated radiosynthesis of [(11)C]harmine for imaging of MAO-A for clinical trials
por: Philippe, C., et al.
Publicado: (2015)

Synthesis and in Silico Evaluation of Novel Compounds for PET-Based Investigations of the Norepinephrine Transporter
por: Neudorfer, Catharina, et al.
Publicado: (2015)

Task-relevant brain networks identified with simultaneous PET/MR imaging of metabolism and connectivity
por: Hahn, Andreas, et al.
Publicado: (2017)

Brain glucose uptake during transcranial direct current stimulation measured with functional [(18)F]FDG-PET
por: Kraus, Christoph, et al.
Publicado: (2019)

Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI
por: Rami-Mark, Christina, et al.
Publicado: (2015)

Small-animal PET evaluation of [(11)C]MC113 as a PET tracer for P-glycoprotein
por: Mairinger, Severin, et al.
Publicado: (2010)

Exploring the Impact of BDNF Val66Met Genotype on Serotonin Transporter and Serotonin-1A Receptor Binding
por: Kraus, Christoph, et al.
Publicado: (2014)

Effects of bilateral sequential theta-burst stimulation on 5-HT(1A) receptors in the dorsolateral prefrontal cortex in treatment-resistant depression: a proof-of-concept trial
por: Murgaš, Matej, et al.
Publicado: (2023)

Association of dopamine D(2/3) receptor binding potential measured using PET and [(11)C]-(+)-PHNO with post-mortem DRD(2/3) gene expression in the human brain
por: Komorowski, Arkadiusz, et al.
Publicado: (2020)

Simultaneous radiomethylation of [(11)C]harmine and [(11)C]DASB and kinetic modeling approach for serotonergic brain imaging in the same individual
por: Vraka, Chrysoula, et al.
Publicado: (2022)

Update on PET Tracer Development for Muscarinic Acetylcholine Receptors
por: Ozenil, Marius, et al.
Publicado: (2021)

Effects of Silexan on the Serotonin-1A Receptor and Microstructure of the Human Brain: A Randomized, Placebo-Controlled, Double-Blind, Cross-Over Study with Molecular and Structural Neuroimaging
por: Baldinger, Pia, et al.
Publicado: (2015)

Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism
por: Berroterán-Infante, Neydher, et al.
Publicado: (2019)

Imaging Biomarkers or Biomarker Imaging?
por: Mitterhauser, Markus, et al.
Publicado: (2014)

CAM-Xenograft Model Provides Preclinical Evidence for the Applicability of [(68)Ga]Ga-Pentixafor in CRC Imaging
por: Benčurová, Katarína, et al.
Publicado: (2022)

Attenuation Correction Approaches for Serotonin Transporter Quantification With PET/MRI
por: Rischka, Lucas, et al.
Publicado: (2019)

PS186. Light exposure and seasonal variation of the serotonin degrading enzyme monoamine oxidase A in the healthy human brain revealed by PET
por: Hienert, Marius, et al.
Publicado: (2016)

Development and evaluation of a rapid analysis for HEPES determination in (68)Ga-radiotracers
por: Pfaff, Sarah, et al.
Publicado: (2018)

Multimodal [(18)F]FDG PET/CT Is a Direct Readout for Inflammatory Bone Repair: A Longitudinal Study in TNFα Transgenic Mice
por: Hayer, Silvia, et al.
Publicado: (2019)

Toward the Optimization of (+)-[(11)C]PHNO Synthesis: Time Reduction and Process Validation
por: Pfaff, Sarah, et al.
Publicado: (2019)

A PET microdosing study with the P-glycoprotein inhibitor tariquidar
por: Bauer, Martin, et al.
Publicado: (2012)

PM478. Imaging the effects of d-amphetamine in the human brain for modelling dopaminergic alterations in schizophrenia
por: Willeit, Matthäus, et al.
Publicado: (2016)

PS168. Hybrid PET/MR imaging of serotonin transporter occupancy and brain activation to elucidate the mechanism of action of selective serotonin reuptake inhibitors
por: Gryglewski, G, et al.
Publicado: (2016)

PS183. Effect of electroconvulsive therapy on monoamine oxidase A binding - a preliminary report
por: Baldinger-Melich, Pia, et al.
Publicado: (2016)

Parcellation of the Human Cerebral Cortex Based on Molecular Targets in the Serotonin System Quantified by Positron Emission Tomography In vivo
por: James, Gregory M, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8tbva0oa21g5437asd5euc5h4q