Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability

Endothelial cells (ECs) play a key role to maintain the functionality of blood vessels. Altered EC permeability causes severe impairment in vessel stability and is a hallmark of pathologies such as cancer and thrombosis. Integrating label-free quantitative proteomics data into genome-wide metabolic...

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Detalles Bibliográficos
Autores principales: Patella, Francesca, Schug, Zachary T., Persi, Erez, Neilson, Lisa J., Erami, Zahra, Avanzato, Daniele, Maione, Federica, Hernandez-Fernaud, Juan R., Mackay, Gillian, Zheng, Liang, Reid, Steven, Frezza, Christian, Giraudo, Enrico, Fiorio Pla, Alessandra, Anderson, Kurt, Ruppin, Eytan, Gottlieb, Eyal, Zanivan, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349982/
https://www.ncbi.nlm.nih.gov/pubmed/25573745
http://dx.doi.org/10.1074/mcp.M114.045575

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